MTHFR Gene Polymorphic Nucleic Acidum
Product nomen
HWTS-GE004-MTHFR Gene Polymorphic Nucleic Acidum Detection Ornamentum (ARMS-PCR)
Epidemiologia
Acidum folicum est Vitaminum aquaticum solubile quod essentiale cofactor est in metabolicis viae corporis.Annis ingentes studiorum numerus confirmaverunt mutationem folatium metabolizationis enzyme gene MTHFR ad defectum acidi folici in corpore deducendum, et damnum commune acidi folici defectus in adultis megaloblasticam anemiam, vascularem causare potest. damnum endotheliale etc. Folic acidum defectus in gravidis mulieribus non possunt occurrere necessitatibus sui et foetus, qui defectibus tubus neuralis, anencephalia, abortus et abortus causare possunt.Serum folatium graduum 5,10-methylenetetrahydrofolatum reductase (MTHFR) polymorphismi afficiuntur.In 677C>T et 1298A>C mutationum generum MTHFR conversionem alaninarum ad acidum valine et glutamicum inducunt, respective, inde in activitatem MTHFR reductam ac proinde acidi folici utendo reduci.
Channel
| FAM | MTHFR C677T |
| ROX | MTHFR A1298C |
| VIC(HEX) | Internum imperium |
Technical Parameters
| Repono | ≤-18℃ |
| Fasciae vita | XII mensibus |
| Specimen Type | Nuper collecta EDTA anticoagulato sanguine |
| CV | ≤5.0% |
| Ct | ≤38 |
| LoD | 1.0ng/μL |
| Instrumenta applicabilia: | Acta Biosystems (VII)D Real-time PCR Systems Acta Biosystems (VII)D Fast Verus-Tempus PCR Systems SLAN ®-96P Real-time PCR Systems QuantStudio™ 5 Real-Time PCR Systems LightCycler®480 Real-time PCR systema LineGene 9600 Plus Real-time PCR Detection System MA-6000 Real-time Quantitatis Thermal Cycler BioRad CFX96 Real-time PCR System BioRad CFX Opus 96 Real-time PCR System |
Opus O
Optio 1
Commendatur extractio reagentium: Macro & Micro-test Genomic DNA Kit (HWTS-3014-32, HWTS-3014-48, HWTS-3014-96) et Macro & Micro-test Automatic Acidum Nucleicum Extractor (HWTS-3006C, HWTS-3006B) .
Optio 2
Commendatur extraction reagentia: Sanguinis Genomic DNA Extraction Kit (YDP348, JCXB20210062) Tiangen Biotech (Beijing) Co.,Ltd.Sanguinis Genome Extraction Ornamentum (A1120) by Promega.
