Mycobacterium Tuberculosis INH Resistentia
Product Name
HWTS-RT002A-Mycobacterium Tuberculosis Isoniazid Resistentia Detection Kit (Fluorescens PCR)
Epidemiologia
Isoniazid, clavis anti-tuberculosis pharmacum anno 1952 introductum, unum ex efficacissimis medicamentis ad tractationem activam tuberculosis coniunctam et unum pharmacum ad tuberculosis latentem.
KatG est gene principale descriptam catalasi-peroxidasem et katG gene mutationis synthesim acidi mycolici parietis cellae promovere potest, bacteria isoniazid renitentem facit.Expressio KatG negative connectitur cum mutationibus in INH-MIC, et diminutio 2-triplex in expressione katG evenit paulo ampliore 2-ovili augmento in MIC.Alia causa resistendi isoniazidorum in mycobacterio tuberculosis occurrit, cum basis insertionis, deletionis vel mutationis occurrit in InhA gene loco mycobacteri tuberculosis.
Channel
ROX | inhA (-15C>T) situs· |
CY5 | katG (315G>C) site |
VIC (HEX) | IS6110 |
Technical Parameters
Repono | ≤-18℃ in tenebris |
Fasciae vita | XII mensibus |
Specimen Type | Sputum |
CV | ≤5.0% |
LoD | 1 103Bacteria/mL * |
Specification | Reactivity-no-crux cum mutationibus quatuor medicamentorum situum resistentium (511, 516, 526 et 531) de rpoB gene extra detectionem range detectionis ornamentum. Instrumenta applicabilia: Acta Biosystems (VII)D Real-time PCR Systems Acta Biosystems (VII)D Fast Verus-Tempus PCR Systems QuantStudio®5 Real-Time PCR Systems SLAN-96P Real-time PCR Systems LightCycler®480 Real-time PCR systema LineGene 9600 Plus Real-time PCR Detection System MA-6000 Real-time Quantitatis Thermal Cycler BioRad CFX96 Real-time PCR System BioRad CFX Opus 96 Real-time PCR System |